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本片根据社会活动家约翰·戴维森的人生经历改编。他年少时被诊断出患有妥瑞氏综合征，会不受控制地抽动身体或口吐恶言。妥瑞氏综合征迫使约翰与同龄人疏远，而他则不懈与这种鲜为人知的症状作斗争，积极为妥瑞氏人群发声。
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露西娅・古铁雷斯是西班牙国民警卫队的一名中士，她正在调查一位邻居离奇的自杀事件，以及在圣周首批花车巡游期间发生的怪异事件。马加莉・卡斯蒂略是美国陆军宪兵队的一名特工，她被派去寻找一名失踪美国士兵的下落，这名士兵似乎与空军基地指挥官道格拉斯・胡彭上校的不正当勾当以及一名卑鄙的海军陆战队队员安德鲁・泰勒中尉有关。她们很快发现，这两起调查是相互关联的。
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To Elena, existence is an effort—not only does she struggle against her body affected by Parkinson’s, but her daughter has just shown up dead and only she finds the suicide hypothesis implausible. Elena is not a good victim, and doesn’t show signs of having been a selfless mother. She is vulnerable, but also overcome by rage and sorrow, and that stubbornness seems to render her invincible, against all odds. But investigating the reasons for her daughter’s death soon becomes a trip through memory, and, as we’ve known since the time of Greek tragedies, every investigation is, deep down, an investigation about oneself. Elena Knows submerges us in the physical and mental experience of its protagonist and, at the same time, invites us to ask ourselves uncomfortable questions about aging, the complexity of mother-daughter bonds and the weight of those mandates women drag the same way Elena drags her feet. 源自：https://www.mardelplatafilmfest.com/38/en/pelicula/elena-sabe